Seidman LJ, Rosso IM, Thermenos HW, Makris N, Juelich R, Gabrieli JD, Faraone SV, Tsuang MT, Whitfield-Gabrieli S Schizophr. Res. 2014 Nov;159(2-3):426-34 PMID: 25308834 Abstract BACKGROUND: Clues to the etiology and pathophysiology of schizophrenia can be examined in their first-degree relatives because they are genetically related to an ill family… read more →
Whitford TJ, Kubicki M, Pelavin PE, Lucia D, Schneiderman JS, Pantelis C, McCarley RW, Shenton ME Schizophr. Res. 2015 Jan;161(1):36-41 PMID: 25311780 Abstract BACKGROUND: Delusions of control are among the most distinctive and characteristic symptoms of schizophrenia. Several theories have been proposed that implicate aberrant communication between spatially disparate brain… read more →
O’Donnell LJ, Pasternak O Schizophr. Res. 2015 Jan;161(1):133-41 PMID: 25278106 Abstract One key pitfall in diffusion magnetic resonance imaging (dMRI) clinical neuroimaging research is the challenge of understanding and interpreting the results of a complex analysis pipeline. The sophisticated algorithms employed by the analysis software, combined with the relatively non-specific… read more →
Wigand M, Kubicki M, Clemm von Hohenberg C, Leicht G, Karch S, Eckbo R, Pelavin PE, Hawley K, Rujescu D, Bouix S, Shenton ME, Mulert C World J. Biol. Psychiatry 2015 Jan;16(1):31-44 PMID: 25224883 Abstract OBJECTIVES: The interhemispheric auditory pathway has been shown to play a crucial role in the… read more →
Fitzsimmons J, Schneiderman JS, Whitford TJ, Swisher T, Niznikiewicz MA, Pelavin PE, Terry DP, Mesholam-Gately RI, Seidman LJ, Goldstein JM, Kubicki M Psychiatry Res 2014 Nov;224(2):124-32 PMID: 25174840 Abstract The goal of this study was to assess integrity of the cingulum bundle in patients diagnosed with first episode schizophrenia, chronic… read more →
Pasternak O, Westin CF, Dahlben B, Bouix S, Kubicki M Schizophr. Res. 2015 Jan;161(1):113-8 PMID: 25126717 Abstract In a previous study we have demonstrated, using a novel diffusion MRI analysis called free-water imaging, that the early stages of schizophrenia are more likely associated with a neuroinflammatory response and less so… read more →
Kates WR, Olszewski AK, Gnirke MH, Kikinis Z, Nelson J, Antshel KM, Fremont W, Radoeva PD, Middleton FA, Shenton ME, Coman IL Schizophr. Res. 2015 Jan;161(1):76-84 PMID: 25066496 Abstract BACKGROUND: The 22q11.2 deletion syndrome (22q11.2DS) is regarded as an etiologically homogenous model for understanding neuroanatomic disruptions associated with a high… read more →
Maier-Hein KH, Westin CF, Shenton ME, Weiner MW, Raj A, Thomann P, Kikinis R, Stieltjes B, Pasternak O Alzheimers Dement 2015 May;11(5):485-493.e2 PMID: 25035154 Abstract BACKGROUND: Brain atrophy in subjects with mild cognitive impairment (MCI) introduces partial volume effects, limiting the sensitivity of diffusion tensor imaging to white matter microstructural… read more →
Savadjiev P, Rathi Y, Bouix S, Smith AR, Schultz RT, Verma R, Westin CF Med Image Anal 2014 Dec;18(8):1349-60 PMID: 25066750 Abstract Current neuroimaging investigation of the white matter typically focuses on measurements derived from diffusion tensor imaging, such as fractional anisotropy (FA). In contrast, imaging studies of the gray… read more →
Rathi Y, Michailovich O, Laun F, Setsompop K, Grant PE, Westin CF Med Image Anal 2014 Oct;18(7):1143-56 PMID: 25047866 Abstract For accurate estimation of the ensemble average diffusion propagator (EAP), traditional multi-shell diffusion imaging (MSDI) approaches require acquisition of diffusion signals for a range of b-values. However, this makes the… read more →