Lepage C, de Pierrefeu A, Koerte IK, Coleman MJ, Pasternak O, Grant G, Marx CE, Morey RA, Flashman LA, George MS, McAllister TW, Andaluz N, Shutter L, Coimbra R, Zafonte RD, Stein MB, Shenton ME, Bouix S Brain Imaging Behav 2018 Jun;12(3):870-881 PMID: 28676987 Abstract Mild traumatic brain injuries (mTBIs)… read more →
Bonne O, Brandes D, Gilboa A, Gomori JM, Shenton ME, Pitman RK, Shalev AY Am J Psychiatry 2001 Aug;158(8):1248-51 PMID: 11481158 Abstract OBJECTIVE: The authors prospectively explored whether a reduction in the volume of the hippocampus occurs in recent trauma survivors who develop posttraumatic stress disorder (PTSD). METHOD: Thirty-seven survivors… read more →
Gurvits TV, Shenton ME, Hokama H, Ohta H, Lasko NB, Gilbertson MW, Orr SP, Kikinis R, Jolesz FA, McCarley RW, Pitman RK Biol. Psychiatry 1996 Dec;40(11):1091-9 PMID: 8931911 Abstract This study used quantitative volumetric magnetic resonance imaging techniques to explore the neuroanatomic correlates of chronic, combat-related posttraumatic stress disorder (PTSD)… read more →
May FS, Chen QC, Gilbertson MW, Shenton ME, Pitman RK Biol. Psychiatry 2004 Mar;55(6):656-8 PMID: 15013837 Abstract BACKGROUND: Abnormally large cavum septum pellucidum has been reported in posttraumatic stress disorder; however, the origin of this association is uncertain. METHODS: We utilized magnetic resonance imaging to measure cavum septum pellucidum in… read more →
Gilbertson MW, Shenton ME, Ciszewski A, Kasai K, Lasko NB, Orr SP, Pitman RK Nat. Neurosci. 2002 Nov;5(11):1242-7 PMID: 12379862 Abstract In animals, exposure to severe stress can damage the hippocampus. Recent human studies show smaller hippocampal volume in individuals with the stress-related psychiatric condition posttraumatic stress disorder (PTSD). Does… read more →
Pitman RK, Gilbertson MW, Gurvits TV, May FS, Lasko NB, Metzger LJ, Shenton ME, Yehuda R, Orr SP, Ann. N. Y. Acad. Sci. 2006 Jul;1071:242-54 PMID: 16891575 Abstract A biological abnormality found to be associated with posttraumatic stress disorder (PTSD) may be, among other things, a pretrauma vulnerability factor, that… read more →
Rauch SL, Shin LM, Segal E, Pitman RK, Carson MA, McMullin K, Whalen PJ, Makris N Neuroreport 2003 May;14(7):913-6 PMID: 12802174 Abstract Different subterritories of anterior cingulate cortex (ACC) and adjacent ventromedial frontal cortex have been shown to serve distinct functions. This scheme has influenced contemporary pathophysiologic models of psychiatric… read more →
Tanev K Curr Psychiatry Rep 2003 Oct;5(5):369-83 PMID: 13678559 Abstract Neurobiologic, psychologic, and social factors interact jointly to create and perpetuate the symptoms of post-traumatic stress disorder (PTSD). The fear conditioning paradigm in animal research helped researchers gather preclinical evidence for the possible contribution of several brain areas to PTSD… read more →
Shin LM, Shin PS, Heckers S, Krangel TS, Macklin ML, Orr SP, Lasko N, Segal E, Makris N, Richert K, Levering J, Schacter DL, Alpert NM, Fischman AJ, Pitman RK, Rauch SL Hippocampus 2004;14(3):292-300 PMID: 15132428 Abstract Recent studies have reported memory deficits and reduced hippocampal volumes in posttraumatic stress… read more →
Greenberg MS, Tanev K, Marin MF, Pitman RK Alzheimers Dement 2014 Jun;10(3 Suppl):S155-65 PMID: 24924667 Abstract The physiological consequences of acute and chronic stress on a range of organ systems have been well documented after the pioneering work of Hans Selye more than 70 years ago. More recently, an association… read more →
