Gracia RI, Levitt JJ, Tsuang MT Psychiatry 1989 Feb;52(1):26-40 PMID: 2928413 Abstract Psychiatric illnesses involve complex interpersonal and biological processes that combine to produce certain clinical signs and symptoms of psychopathology on which psychiatric diagnostics are based. Nevertheless, the clinical presentation of some psychiatric disorders may vary from patient to… read more →
Nazeri A, Chakravarty MM, Rotenberg DJ, Rajji TK, Rathi Y, Michailovich OV, Voineskos AN J. Neurosci. 2015 Jan;35(4):1753-62 PMID: 25632148 Abstract As humans age, a characteristic pattern of widespread neocortical dendritic disruption coupled with compensatory effects in hippocampus and other subcortical structures is shown in postmortem investigations. It is now… read more →
Walhovd KB, Fjell AM, Reinvang I, Lundervold A, Dale AM, Eilertsen DE, Quinn BT, Salat D, Makris N, Fischl B Neurobiol. Aging 2005 Oct;26(9):1261-70; discussion 1275-8 PMID: 16005549 Abstract The effect of age was investigated in and compared across 16 automatically segmented brain measures: cortical gray matter, cerebral white matter,… read more →
Bush G, Spencer TJ, Holmes J, Shin LM, Valera EM, Seidman LJ, Makris N, Surman C, Aleardi M, Mick E, Biederman J Arch. Gen. Psychiatry 2008 Jan;65(1):102-14 PMID: 18180434 Abstract CONTEXT: Previous studies have reported hypofunction, structural abnormalities, and biochemical abnormalities of the dorsal anterior midcingulate cortex (daMCC) in attention-deficit/hyperactivity… read more →
Lopez-Larson M, Michael ES, Terry JE, Breeze JL, Hodge SM, Tang L, Kennedy DN, Moore CM, Makris N, Caviness VS, Frazier JA J Child Adolesc Psychopharmacol 2009 Feb;19(1):31-9 PMID: 19232021 Abstract INTRODUCTION: A significant number of children with bipolar disorder (BP) have co-morbid attention-deficit/hyperactivity disorder (ADHD). It is unknown if… read more →
Monuteaux MC, Seidman LJ, Faraone SV, Makris N, Spencer T, Valera E, Brown A, Bush G, Doyle AE, Hughes S, Helliesen M, Mick E, Biederman J Am. J. Med. Genet. B Neuropsychiatr. Genet. 2008 Dec;147B(8):1436-41 PMID: 18951431 Abstract An emerging literature has demonstrated an association between the dopamine D4 receptor… read more →
Brown AB, Biederman J, Valera EM, Doyle AE, Bush G, Spencer T, Monuteaux MC, Mick E, Whitfield-Gabrieli S, Makris N, LaViolette PS, Oscar-Berman M, Faraone SV, Seidman LJ Am. J. Med. Genet. B Neuropsychiatr. Genet. 2010 Mar;153B(2):365-75 PMID: 19676101 Abstract Although attention-deficit/hyperactivity disorder (ADHD) is associated both with brain alterations… read more →
Makris N, Seidman LJ, Valera EM, Biederman J, Monuteaux MC, Kennedy DN, Caviness VS, Bush G, Crum K, Brown AB, Faraone SV J Atten Disord 2010 Jan;13(4):407-13 PMID: 20008822 Abstract OBJECTIVE: We sought to examine preliminary results of brain alterations in anterior cingulate cortex (ACC) in treatment-naïve adults with ADHD.… read more →
Valera EM, Spencer RM, Zeffiro TA, Makris N, Spencer TJ, Faraone SV, Biederman J, Seidman LJ Biol. Psychiatry 2010 Aug;68(4):359-67 PMID: 20619827 Abstract BACKGROUND: Timing abilities are critical to the successful management of everyday activities and personal safety, and timing abnormalities have been argued to be fundamental to impulsiveness, a… read more →
Spencer TJ, Brown A, Seidman LJ, Valera EM, Makris N, Lomedico A, Faraone SV, Biederman J J Clin Psychiatry 2013 Sep;74(9):902-17 PMID: 24107764 Abstract OBJECTIVE: To evaluate the impact of therapeutic oral doses of stimulants on the brains of ADHD subjects as measured by magnetic resonance imaging (MRI)-based neuroimaging studies… read more →
