Pasternak O, Westin CF, Bouix S, Seidman LJ, Goldstein JM, Woo TU, Petryshen TL, Mesholam-Gately RI, McCarley RW, Kikinis R, Shenton ME, Kubicki M J. Neurosci. 2012 Nov;32(48):17365-72 PMID: 23197727 Abstract Diffusion MRI has been successful in identifying the existence of white matter abnormalities in schizophrenia in vivo. However, the… read more →
Kwon JS, Shenton ME, Hirayasu Y, Salisbury DF, Fischer IA, Dickey CC, Yurgelun-Todd D, Tohen M, Kikinis R, Jolesz FA, McCarley RW Am J Psychiatry 1998 Apr;155(4):509-15 PMID: 9545997 Abstract OBJECTIVE: A cavum between the septi pellucidi may reflect neurodevelopmental anomalies in midline structures of the brain. The authors examined… read more →
McCarley RW, Niznikiewicz MA, Salisbury DF, Nestor PG, O’Donnell BF, Hirayasu Y, Grunze H, Greene RW, Shenton ME Eur Arch Psychiatry Clin Neurosci 1999;249 Suppl 4:69-82 PMID: 10654112 Abstract Seeking to unite psychological and biological approaches, this paper links cognitive and cellular hypotheses and data about thought and language abnormalities… read more →
Shenton ME, Dickey CC, Frumin M, McCarley RW Schizophr. Res. 2001 Apr;49(1-2):1-52 PMID: 11343862 Abstract After more than 100 years of research, the neuropathology of schizophrenia remains unknown and this is despite the fact that both Kraepelin (1919/1971: Kraepelin, E., 1919/1971. Dementia praecox. Churchill Livingston Inc., New York) and Bleuler… read more →
Salisbury DF, Shenton ME, Griggs CB, Bonner-Jackson A, McCarley RW Arch. Gen. Psychiatry 2002 Aug;59(8):686-94 PMID: 12150644 Abstract BACKGROUND: Mismatch negativity (MMN) is an event-related brain potential that is sensitive to stimulus deviation from a repetitive pattern. The MMN is thought primarily to reflect the activity of sensory memory, with,… read more →
Kubicki M, McCarley RW, Shenton ME Curr Opin Psychiatry 2005 Mar;18(2):121-34 PMID: 16639164 Abstract PURPOSE OF REVIEW: The purpose of this review is to highlight important recent imaging, histological, and genetic findings relevant to white matter abnormalities in schizophrenia. It is cast within the context of research findings conducted over… read more →
Kubicki M, Shenton ME Curr Opin Psychiatry 2014 May;27(3):179-84 PMID: 24613986 Abstract PURPOSE OF REVIEW: Schizophrenia is a multifocal brain disease that involves abnormal brain connectivity. Diffusion Tensor Imaging is the most advanced imaging technique to investigate white matter connections in vivo. In this review, we focus on studies published… read more →
Seidman LJ, Faraone SV, Goldstein JM, Goodman JM, Kremen WS, Toomey R, Tourville J, Kennedy D, Makris N, Caviness VS, Tsuang MT Biol. Psychiatry 1999 Oct;46(7):941-54 PMID: 10509177 Abstract BACKGROUND: Schizophrenia is characterized by subcortical and cortical brain abnormalities. Evidence indicates that some nonpsychotic relatives of schizophrenic patients manifest biobehavioral… read more →
Thermenos HW, Keshavan MS, Juelich RJ, Molokotos E, Whitfield-Gabrieli S, Brent BK, Makris N, Seidman LJ Am. J. Med. Genet. B Neuropsychiatr. Genet. 2013 Oct;162B(7):604-35 PMID: 24132894 Abstract In an effort to identify the developing abnormalities preceding psychosis, Dr. Ming T. Tsuang and colleagues at Harvard expanded Meehl’s concept of… read more →
Seidman LJ, Faraone SV, Goldstein JM, Kremen WS, Horton NJ, Makris N, Toomey R, Kennedy D, Caviness VS, Tsuang MT Arch. Gen. Psychiatry 2002 Sep;59(9):839-49 PMID: 12215084 Abstract BACKGROUND: Clues to the causes of schizophrenia can be derived from studying first-degree relatives because they are genetically related to an ill… read more →