Goldstein JM, Seidman LJ, O’Brien LM, Horton NJ, Kennedy DN, Makris N, Caviness VS, Faraone SV, Tsuang MT Arch. Gen. Psychiatry 2002 Feb;59(2):154-64 PMID: 11825137 Abstract BACKGROUND: Previous studies suggest that the impact of early insults predisposing to schizophrenia may have differential consequences by sex. We hypothesized that brain regions… read more →
Seidman LJ, Pantelis C, Keshavan MS, Faraone SV, Goldstein JM, Horton NJ, Makris N, Falkai P, Caviness VS, Tsuang MT Schizophr Bull 2003;29(4):803-30 PMID: 14989416 Abstract A central question in schizophrenia research is which brain abnormalities are independent of psychosis and which evolve before and after psychosis begins. This question… read more →
Sun J, Tang Y, Lim KO, Wang J, Tong S, Li H, He B IEEE Trans Biomed Eng 2014 Jun;61(6):1756-64 PMID: 24845286 Abstract Neuronal oscillations reflect the activity of neuronal ensembles engaged in integrative cognition, and may serve as a functional measure for the cognitive impairment in schizophrenia. This study… read more →
Manoach DS, White N, Lindgren KA, Heckers S, Coleman MJ, Dubal S, Goff DC, Holzman PS Schizophr. Res. 2005 Oct;78(1):1-12 PMID: 16076549 Abstract OBJECTIVE: Using functional MRI, we investigated whether, like healthy subjects, patients with schizophrenia show a relative hemispheric specialization in ventrolateral prefrontal cortex (PFC) for spatial and shape… read more →
Coleman MJ, Levy DL, Lenzenweger MF, Holzman PS J Abnorm Psychol 1996 Aug;105(3):469-73 PMID: 8772019 Abstract Empirical links between schizophrenia and schizotypic psychopathology were examined. The Perceptual Aberration Scale (PerAb; L. J. Chapman, J. O. Chapman, & M. L. Raulin, 1978) was used to identify putative schizotypic individuals and a… read more →
Coleman MJ, Cook S, Matthysse S, Barnard J, Lo Y, Levy DL, Rubin DB, Holzman PS J Abnorm Psychol 2002 Aug;111(3):425-35 PMID: 12150418 Abstract This study reports evidence that schizophrenia patients are significantly impaired in both spatial and object (shape) working memory. A 3-s delay between exposure and recall of… read more →
Levy DL, Coleman MJ, Sung H, Ji F, Matthysse S, Mendell NR, Titone D J Neurolinguistics 2010 May;23(3):176 PMID: 20161689 Abstract Thought disorder as well as language and communication disturbances are associated with schizophrenia and are over-represented in clinically unaffected relatives of schizophrenics. All three kinds of dysfunction involve some… read more →
Levitt JJ, Bobrow L, Lucia D, Srinivasan P Curr Top Behav Neurosci 2010;4:243-81 PMID: 21312403 Abstract Brain imaging studies have long supported that schizophrenia is a disorder of the brain, involving many discrete and widely spread regions. Generally, studies have shown decreases in cortical gray matter (GM) volume. Here, we… read more →
Goff DC, Tsai G, Levitt J, Amico E, Manoach D, Schoenfeld DA, Hayden DL, McCarley R, Coyle JT Arch. Gen. Psychiatry 1999 Jan;56(1):21-7 PMID: 9892252 Abstract BACKGROUND: In a preliminary dose-finding study, D-cycloserine, a partial agonist at the glycine modulatory site of the glutamatergic N-methyl-D-aspartate (NMDA) receptor, improved negative symptoms… read more →
Mandl RC, Pasternak O, Cahn W, Kubicki M, Kahn RS, Shenton ME, Hulshoff Pol HE Schizophr. Res. 2015 Jan;161(1):126-32 PMID: 25454797 Abstract Diffusion weighted imaging (DWI) has been extensively used to study the microarchitecture of white matter in schizophrenia. However, popular DWI-derived measures such as fractional anisotropy (FA) may be… read more →
