Rosenberger G, Nestor PG, Oh JS, Levitt JJ, Kindleman G, Bouix S, Fitzsimmons J, Niznikiewicz M, Westin CF, Kikinis R, McCarley RW, Shenton ME, Kubicki M Brain Imaging Behav 2012 Sep;6(3):417-25 PMID: 22415192 Abstract Thalamo-cortical feedback loops play a key role in the processing and coordination of processing and integration… read more →
Nestor PG, Kubicki M, Nakamura M, Niznikiewicz M, Levitt JJ, Shenton ME, McCarley RW Brain Imaging Behav 2013 Mar;7(1):68-76 PMID: 23011383 Abstract We examined variability in performance on widely-used neuropsychological Wechsler tests of intelligence and memory in a large sample of persons with chronic schizophrenia, a subset of whom had… read more →
Fitzsimmons J, Kubicki M, Shenton ME Curr Opin Psychiatry 2013 Mar;26(2):172-87 PMID: 23324948 Abstract PURPOSE OF REVIEW: We review diffusion tensor imaging (DTI) studies that investigate white matter abnormalities in patients with chronic schizophrenia, first episode schizophrenia, and those who are at genetic risk for developing schizophrenia. Additionally, we include… read more →
Kubicki M, Shenton ME Curr Opin Psychiatry 2014 May;27(3):179-84 PMID: 24613986 Abstract PURPOSE OF REVIEW: Schizophrenia is a multifocal brain disease that involves abnormal brain connectivity. Diffusion Tensor Imaging is the most advanced imaging technique to investigate white matter connections in vivo. In this review, we focus on studies published… read more →
Hüttlova J, Kikinis Z, Kerkovsky M, Bouix S, Vu MA, Makris N, Shenton ME, Kasparek T Cerebellum 2014 Aug;13(4):415-24 PMID: 24550129 Abstract Deficits in the execution of a sequence of movements are common in schizophrenia. Previous studies reported reduced functional activity in the motor cortex and cerebellum in schizophrenic patients… read more →
Venkataraman A, Rathi Y, Kubicki M, Westin CF, Golland P Med Image Comput Comput Assist Interv 2010;13(Pt 1):191-9 PMID: 20879231 Abstract We propose a novel probabilistic framework to merge information from DWI tractography and resting-state fMRI correlations. In particular, we model the interaction of latent anatomical and functional connectivity templates… read more →
Savadjiev P, Rathi Y, Bouix S, Smith AR, Schultz RT, Verma R, Westin CF Med Image Comput Comput Assist Interv 2013;16(Pt 1):50-7 PMID: 24505648 Abstract Despite the fact that several theories link cortical development and function to the development of white matter and its geometrical structure, the relationship between gray… read more →
Ungar L, Nestor PG, Niznikiewicz MA, Wible CG, Kubicki M Psychiatry Res 2010 Jan;181(1):24-9 PMID: 19963356 Abstract Disturbances in selective attention represent a core characteristic of schizophrenia, whose neural underpinnings have yet to be fully elucidated. Consequently, we recorded brain activation using functional magnetic resonance imaging (fMRI) while 15 patients… read more →
Functional and anatomical connectivity abnormalities in left inferior frontal gyrus in schizophrenia
Jeong B, Wible CG, Hashimoto R, Kubicki M Hum Brain Mapp 2009 Dec;30(12):4138-51 PMID: 19569073 Abstract Functional studies in schizophrenia demonstrate prominent abnormalities within the left inferior frontal gyrus (IFG) and also suggest the functional connectivity abnormalities in language network including left IFG and superior temporal gyrus during semantic processing.… read more →
Goldstein JM, Goodman JM, Seidman LJ, Kennedy DN, Makris N, Lee H, Tourville J, Caviness VS, Faraone SV, Tsuang MT Arch. Gen. Psychiatry 1999 Jun;56(6):537-47 PMID: 10359468 Abstract BACKGROUND: Relatively few magnetic resonance imaging studies of schizophrenia have investigated the entire cerebral cortex. Most focus on only a few areas… read more →