Maddah M, Kubicki M, Wells WM, Westin CF, Shenton ME, Grimson WE Med Image Comput Comput Assist Interv 2008;11(Pt 1):917-24 PMID: 18979833 Abstract This paper presents a tract-oriented analysis of diffusion tensor (DT) images of the human brain. We demonstrate that unlike the commonly used ROI-based methods for population studies,… read more →
Oh JS, Kubicki M, Rosenberger G, Bouix S, Levitt JJ, McCarley RW, Westin CF, Shenton ME Hum Brain Mapp 2009 Nov;30(11):3812-25 PMID: 19449328 Abstract Diffusion tensor imaging (DTI) and fiber tractography are useful tools for reconstructing white matter tracts (WMT) in the brain. Previous tractography studies have sought to segment… read more →
Nestor PG, Kubicki M, Nakamura M, Niznikiewicz M, McCarley RW, Shenton ME Neuropsychology 2010 Jan;24(1):121-9 PMID: 20063953 Abstract The authors examined the relationship between neuropsychological performance and MRI of the orbital frontal cortex (OFC) and diffusion tensor imaging (DTI) of the cingulum bundle (CB) within groups of patients with schizophrenia… read more →
Kubicki M, Niznikiewicz M, Connor E, Ungar L, Nestor P, Bouix S, Dreusicke M, Kikinis R, McCarley R, Shenton ME Brain Imaging Behav 2009 Jun;3(2):191-201 PMID: 20556231 Abstract Attention and memory deficits are among the most prominent cognitive disturbances observed in schizophrenia. It has been suggested that a disruption in… read more →
Nguyen AD, Shenton ME, Levitt JJ Harv Rev Psychiatry 2010 Sep-Oct;18(5):279-92 PMID: 20825265 Abstract Olfactory processing is thought to be mediated via the frontal and temporolimbic brain regions, both of which, as well as olfactory dysfunction, are implicated in schizophrenia. Likewise, several empirical studies of olfactory dysfunction–in particular, olfactory deficits… read more →
Spencer KM, Nestor PG, Valdman O, Niznikiewicz MA, Shenton ME, McCarley RW Neuropsychology 2011 Jan;25(1):76-85 PMID: 20919764 Abstract OBJECTIVE: While attentional functions are usually found to be impaired in schizophrenia, a review of the literature on the orienting of spatial attention in schizophrenia suggested that voluntary attentional orienting in response… read more →
Shenton ME, Whitford TJ, Kubicki M Dialogues Clin Neurosci 2010;12(3):317-32 PMID: 20954428 Abstract Historically, Kraepelin speculated that dementia praecox resulted from damage to the cerebral cortex, most notably the frontal and temporal cortices. It is only recently, however, that tools have been available to test this hypothesis. Now, more than… read more →
Nguyen AD, Pelavin PE, Shenton ME, Chilakamarri P, McCarley RW, Nestor PG, Levitt JJ Brain Imaging Behav 2011 Dec;5(4):252-61 PMID: 21728040 Abstract The current report used structural magnetic resonance imaging (MRI) to objectively measure olfactory bulb volume and olfactory sulcal depth in patients diagnosed with chronic schizophrenia and healthy controls.… read more →
Melonakos ED, Shenton ME, Rathi Y, Terry DP, Bouix S, Kubicki M Psychiatry Res 2011 Aug;193(2):65-70 PMID: 21684124 Abstract Voxel-based morphometry (VBM) is a hypothesis-free, whole-brain, voxel-by-voxel analytic method that attempts to compare imaging data between populations. Schizophrenia studies have utilized this method to localize differences in diffusion tensor imaging… read more →
Uehara-Aoyama K, Nakamura M, Asami T, Yoshida T, Hayano F, Roppongi T, Fujiwara A, Inoue T, Shenton ME, Hirayasu Y Psychiatry Clin. Neurosci. 2011 Aug;65(5):483-9 PMID: 21851457 Abstract AIM: The sulcogyral pattern of the orbitofrontal cortex (OFC) is characterized by a remarkable inter-individual variability that likely reflects neurobehavioral traits and… read more →