A preliminary morphometric magnetic resonance imaging study of regional brain volumes in body dysmorphic disorder

Rauch SL, Phillips KA, Segal E, Makris N, Shin LM, Whalen PJ, Jenike MA, Caviness VS, Kennedy DN

Psychiatry Res 2003 Jan;122(1):13-9

PMID: 12589879


Morphometric magnetic resonance imaging (MRI) was used to compare regional brain volumes in eight women with body dysmorphic disorder (BDD) and eight healthy comparison subjects. The BDD group exhibited a relative leftward shift in caudate asymmetry and greater total white matter vs. the comparison group. Findings with respect to the caudate nucleus are consistent with both the conceptualization of BDD as an obsessive-compulsive spectrum disorder, and the ‘striatal topography model’ of obsessive-compulsive disorders.