Psychiatry Neuroimaging Laboratory | PNL

Our mission is to investigate brain abnormalities in neuropsychiatric disorders using more precise and accurate techniques. This is important when brain abnormalities are subtle and hard to detect, such as in schizophrenia and mild traumatic brain injury. This new technology will lead to new discoveries and to improved treatments. We welcome trainees from around the world. Read more

Mission

Tractography

A 3D modeling
technique used
to represent
visually neural
tracts.
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Mission

Our mission is to investigate brain abnormalities in neuropsychiatric disorders using more precise and accurate techniques. This is important when brain abnormalities are subtle and hard to detect, such as in schizophrenia and mild traumatic brain injury. This new technology will lead to new discoveries and to improved treatments. We welcome trainees from around the world. Read more

DTI

White matter
fiber bundles
illustrated in
3D and derived
from Diffusion
Tensor Imaging.
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Mission

Our mission is to investigate brain abnormalities in neuropsychiatric disorders using more precise and accurate techniques. This is important when brain abnormalities are subtle and hard to detect, such as in schizophrenia and mild traumatic brain injury. This new technology will lead to new discoveries and to improved treatments. We welcome trainees from around the world. Read more

Fiber Tracts

3D Visualization of
white matter fiber
bundles in the brain
created using an
automatic clustering
algorithm
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(Visualization in Medicine and Life Sciences. Mathematics and Visualization 2008, pp 173-184)
Mission

Our mission is to investigate brain abnormalities in neuropsychiatric disorders using more precise and accurate techniques. This is important when brain abnormalities are subtle and hard to detect, such as in schizophrenia and mild traumatic brain injury. This new technology will lead to new discoveries and to improved treatments. We welcome trainees from around the world. Read more

Shape Analysis

Morphometric features
of the brain include
volume, area, and shape.
Here we show shape
changes in caudate
nucleus in
schizophrenia spectrum.
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Mission

Our mission is to investigate brain abnormalities in neuropsychiatric disorders using more precise and accurate techniques. This is important when brain abnormalities are subtle and hard to detect, such as in schizophrenia and mild traumatic brain injury. This new technology will lead to new discoveries and to improved treatments. We welcome trainees from around the world. Read more

Corpus Callosum

The largest bundle
of white matter
fibers in the brain,
created using
Two-Tensor
Tractography.
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(Koerte & Muehlmann, Ch. 5 in Mulert & Shenton’s MRI in Psychiatry)
Mission

Our mission is to investigate brain abnormalities in neuropsychiatric disorders using more precise and accurate techniques. This is important when brain abnormalities are subtle and hard to detect, such as in schizophrenia and mild traumatic brain injury. This new technology will lead to new discoveries and to improved treatments. We welcome trainees from around the world. Read more

MRS

Magnetic Resonance
Spectroscopy is an
imaging technique that
shows brain metabolites.
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Mission

Our mission is to investigate brain abnormalities in neuropsychiatric disorders using more precise and accurate techniques. This is important when brain abnormalities are subtle and hard to detect, such as in schizophrenia and mild traumatic brain injury. This new technology will lead to new discoveries and to improved treatments. We welcome trainees from around the world. Read more

Beautiful Brain

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Lab News

Accelerating Medicines Partnership – Schizophrenia (AMP SCZ) Data Repository

December 14, 2021

Brigham Researchers Awarded Two Prestigious NIH Grants

December 8, 2020

NIH public-private partnership to advance early interventions for schizophrenia

November 18, 2020

Review of the application of neuroimaging techniques to study neuropsychiatric disorders

September 2, 2020

Textbook on the use of MRI in psychiatry

September 2, 2020

General News

NCAA offers settlement in athlete concussion cases

July 31, 2014

Message from the PNL Director

Visualizing White Matter

Cortical Spinal Tract (Yellow) and
Cingulum Bundle (Red)

Research Area

Chronic Schizophrenia

A new generation of MR im...

Traumatic Brain Injury

Our group began research ...

First Episode Schizophrenia

Magnetic resonance imagin...

Education

NIMH Director’s Message: Accelerating Science to Advance Early Interventions for Schizophrenia

November 6, 2020

NPR: US Science Suffering From Booms And Busts in Funding

September 9, 2014

NPR: When Scientists Give Up

September 9, 2014

People

Martha E. Shenton, Ph.D.

July 9, 2014

Marek Kubicki, M.D., Ph.D.

July 8, 2014

Sylvain Bouix, Ph.D.

July 8, 2014

Yogesh Rathi, Ph.D.

August 26, 2014