Voineskos AN, Rajji TK, Lobaugh NJ, Miranda D, Shenton ME, Kennedy JL, Pollock BG, Mulsant BH Neurobiol. Aging 2012 Jan;33(1):21-34 PMID: 20363050 Abstract Age-related decline in microstructural integrity of certain white matter tracts may explain cognitive decline associated with normal aging. Whole brain tractography and a clustering segmentation in 48… read more →
Vaswani N, Rathi Y, Yezzi A, Tannenbaum A IEEE Trans Image Process 2010 Apr;19(4):841-57 PMID: 19933014 Abstract We propose algorithms for tracking the boundary contour of a deforming object from an image sequence, when the nonaffine (local) deformation over consecutive frames is large and there is overlapping clutter, occlusions, low… read more →
Malcolm JG, Michailovich O, Bouix S, Westin CF, Shenton ME, Rathi Y Med Image Anal 2010 Feb;14(1):58-69 PMID: 19914856 Abstract We propose a technique to simultaneously estimate the local fiber orientations and perform multi-fiber tractography. Existing techniques estimate the local fiber orientation at each voxel independently so there is no… read more →
Fitzsimmons J, Kubicki M, Smith K, Bushell G, Estepar RS, Westin CF, Nestor PG, Niznikiewicz MA, Kikinis R, McCarley RW, Shenton ME Schizophr. Res. 2009 Jan;107(1):39-46 PMID: 19046624 Abstract BACKGROUND: White matter fiber tracts, especially those interconnecting the frontal and temporal lobes, are likely implicated in pathophysiology of schizophrenia. Very… read more →
Kubicki M, Styner M, Bouix S, Gerig G, Markant D, Smith K, Kikinis R, McCarley RW, Shenton ME Schizophr. Res. 2008 Dec;106(2-3):125-31 PMID: 18829262 Abstract BACKGROUND: A reduction in interhemispheric connectivity is thought to contribute to the etiology of schizophrenia. Diffusion Tensor Imaging (DTI) measures the diffusion of water and… read more →
Pasternak O, Assaf Y, Intrator N, Sochen N Magn Reson Imaging 2008 Oct;26(8):1133-44 PMID: 18524529 Abstract Partial volume effects are often experienced in diffusion-weighted MRI of biologic tissue. This is when the signal attenuation reflects a mixture of diffusion processes, originating from different tissue compartments, residing in the same voxel.… read more →
Savadjiev P, Campbell JS, Descoteaux M, Deriche R, Pike GB, Siddiqi K Neuroimage 2008 May;41(1):58-68 PMID: 18367409 Abstract Whereas high angular resolution reconstruction methods for diffusion MRI can estimate multiple dominant fibre orientations within a single imaging voxel, they are fundamentally limited in certain cases of complex subvoxel fibre structures,… read more →
Savadjiev P, Campbell JS, Pike GB, Siddiqi K Med Image Anal 2006 Oct;10(5):799-813 PMID: 16919994 Abstract We develop a differential geometric framework for regularizing diffusion MRI data. The key idea is to model white matter fibres as 3D space curves and to then extend Parent and Zucker’s 2D curve inference… read more →