Kubicki M, Park H, Westin CF, Nestor PG, Mulkern RV, Maier SE, Niznikiewicz M, Connor EE, Levitt JJ, Frumin M, Kikinis R, Jolesz FA, McCarley RW, Shenton ME Neuroimage 2005 Jul;26(4):1109-18 PMID: 15878290 Abstract Diffusion tensor imaging (DTI) studies in schizophrenia demonstrate lower anisotropic diffusion within white matter due either… read more →
Kubicki M, Westin CF, McCarley RW, Shenton ME Ann. N. Y. Acad. Sci. 2005 Dec;1064:134-48 PMID: 16394153 Abstract Schizophrenia is a serious and disabling mental disorder that affects approximately 1% of the general population, with often devastating effects on the psychological and financial resources of the patient, family, and larger… read more →
Kubicki M, McCarley RW, Shenton ME Curr Opin Psychiatry 2005 Mar;18(2):121-34 PMID: 16639164 Abstract PURPOSE OF REVIEW: The purpose of this review is to highlight important recent imaging, histological, and genetic findings relevant to white matter abnormalities in schizophrenia. It is cast within the context of research findings conducted over… read more →
Nestor PG, Kubicki M, Niznikiewicz M, Gurrera RJ, McCarley RW, Shenton ME Neuropsychology 2008 Mar;22(2):246-54 PMID: 18331167 Abstract Patients with schizophrenia and healthy control subjects underwent both neuropsychological evaluation and magnetic resonance diffusion tensor imaging, during which the cingulum bundle (CB) and the uncinate fasciculus (UF) were defined with fiber… read more →
Maddah M, Kubicki M, Wells WM, Westin CF, Shenton ME, Grimson WE Med Image Comput Comput Assist Interv 2008;11(Pt 1):917-24 PMID: 18979833 Abstract This paper presents a tract-oriented analysis of diffusion tensor (DT) images of the human brain. We demonstrate that unlike the commonly used ROI-based methods for population studies,… read more →
Nestor PG, Kubicki M, Nakamura M, Niznikiewicz M, McCarley RW, Shenton ME Neuropsychology 2010 Jan;24(1):121-9 PMID: 20063953 Abstract The authors examined the relationship between neuropsychological performance and MRI of the orbital frontal cortex (OFC) and diffusion tensor imaging (DTI) of the cingulum bundle (CB) within groups of patients with schizophrenia… read more →
Kubicki M, Niznikiewicz M, Connor E, Ungar L, Nestor P, Bouix S, Dreusicke M, Kikinis R, McCarley R, Shenton ME Brain Imaging Behav 2009 Jun;3(2):191-201 PMID: 20556231 Abstract Attention and memory deficits are among the most prominent cognitive disturbances observed in schizophrenia. It has been suggested that a disruption in… read more →
Rosenberger G, Nestor PG, Oh JS, Levitt JJ, Kindleman G, Bouix S, Fitzsimmons J, Niznikiewicz M, Westin CF, Kikinis R, McCarley RW, Shenton ME, Kubicki M Brain Imaging Behav 2012 Sep;6(3):417-25 PMID: 22415192 Abstract Thalamo-cortical feedback loops play a key role in the processing and coordination of processing and integration… read more →
Kubicki M, Shenton ME Curr Opin Psychiatry 2014 May;27(3):179-84 PMID: 24613986 Abstract PURPOSE OF REVIEW: Schizophrenia is a multifocal brain disease that involves abnormal brain connectivity. Diffusion Tensor Imaging is the most advanced imaging technique to investigate white matter connections in vivo. In this review, we focus on studies published… read more →
Hüttlova J, Kikinis Z, Kerkovsky M, Bouix S, Vu MA, Makris N, Shenton ME, Kasparek T Cerebellum 2014 Aug;13(4):415-24 PMID: 24550129 Abstract Deficits in the execution of a sequence of movements are common in schizophrenia. Previous studies reported reduced functional activity in the motor cortex and cerebellum in schizophrenic patients… read more →
