Seidman LJ, Valera EM, Makris N Biol. Psychiatry 2005 Jun;57(11):1263-72 PMID: 15949998 Abstract Many investigators have hypothesized that attention-deficit/hyperactivity disorder (ADHD) involves structural and functional brain abnormalities in frontal-striatal circuitry. Although our review suggests that there is substantial support for this hypothesis, a growing literature demonstrates widespread abnormalities affecting other… read more →
Makris N, Kennedy DN, McInerney S, Sorensen AG, Wang R, Caviness VS, Pandya DN Cereb. Cortex 2005 Jun;15(6):854-69 PMID: 15590909 Abstract Previous research in non-human primates has shown that the superior longitudinal fascicle (SLF), a major intrahemispheric fiber tract, is actually composed of four separate components. In humans, only post-mortem… read more →
Herbert MR, Ziegler DA, Deutsch CK, O’Brien LM, Kennedy DN, Filipek PA, Bakardjiev AI, Hodgson J, Takeoka M, Makris N, Caviness VS Brain 2005 Jan;128(Pt 1):213-26 PMID: 15563515 Abstract We report a whole-brain MRI morphometric survey of asymmetry in children with high-functioning autism and with developmental language disorder (DLD). Subjects… read more →
Spencer KM, Nestor PG, Perlmutter R, Niznikiewicz MA, Klump MC, Frumin M, Shenton ME, McCarley RW Proc. Natl. Acad. Sci. U.S.A. 2004 Dec;101(49):17288-93 PMID: 15546988 Abstract Current views of schizophrenia suggest that it results from abnormalities in neural circuitry, but empirical evidence in the millisecond range of neural activity has… read more →
del Re E, Sidis Y, Fabrizio DA, Lin HY, Schneyer A J. Biol. Chem. 2004 Dec;279(51):53126-35 PMID: 15475360 Abstract Activins and inhibins compose a heterogeneous subfamily within the transforming growth factor-beta (TGF-beta) superfamily of growth and differentiation factors with critical biological activities in embryos and adults. They signal through a… read more →
Haseler LJ, Lin AP, Richardson RS J. Appl. Physiol. 2004 Sep;97(3):1077-81 PMID: 15133010 Abstract Previously, it was demonstrated in exercise-trained humans that phosphocreatine (PCr) recovery is significantly altered by fraction of inspired O2 (FI(O2)), suggesting that in this population under normoxic conditions, O2 availability limits maximal oxidative rate. Haseler LJ,… read more →
del Re E, Babitt JL, Pirani A, Schneyer AL, Lin HY J. Biol. Chem. 2004 May;279(21):22765-72 PMID: 14996829 Abstract Transforming growth factor beta (TGF-beta) ligands exert their biological effects through type II (TbetaRII) and type I receptors (TbetaRI). Unlike TGF-beta1 and -beta3, TGF-beta2 appears to require the co-receptor betaglycan (type… read more →