Kubicki M, Westin CF, Maier SE, Frumin M, Nestor PG, Salisbury DF, Kikinis R, Jolesz FA, McCarley RW, Shenton ME Am J Psychiatry 2002 May;159(5):813-20 PMID: 11986136 Abstract OBJECTIVE: Disruptions in connectivity between the frontal and temporal lobes may explain some of the symptoms observed in schizophrenia. Conventional magnetic resonance… read more →
Anderson JE, Wible CG, McCarley RW, Jakab M, Kasai K, Shenton ME Schizophr. Res. 2002 Dec;58(2-3):123-34 PMID: 12409152 Abstract Previous magnetic resonance imaging (MRI) studies have reported various subtle brain abnormalities in schizophrenic patients, including temporal lobe abnormalities, which are of particular interest given the role of this brain region… read more →
Salisbury DF, Shenton ME, Griggs CB, Bonner-Jackson A, McCarley RW Arch. Gen. Psychiatry 2002 Aug;59(8):686-94 PMID: 12150644 Abstract BACKGROUND: Mismatch negativity (MMN) is an event-related brain potential that is sensitive to stimulus deviation from a repetitive pattern. The MMN is thought primarily to reflect the activity of sensory memory, with,… read more →
Anderson JE, O’Donnell BF, McCarley RW, Shenton ME Restor. Neurol. Neurosci. 1998 Jun;12(2-3):175-84 PMID: 12671313 Abstract Schizophrenia is a disorder characterized by multiple symptoms, with a varied course and outcome. The etiology is yet unknown, but multiple pathological processes or, equally likely, a unique pathophysiological process, may be involved. Here,… read more →
O’Donnell BF, Potts GF, Nestor PG, Stylianopoulos KC, Shenton ME, McCarley RW J Abnorm Psychol 2002 Nov;111(4):620-5 PMID: 12428775 Abstract Pathways within the visual system can be distinguished on the basis of selectivity for low or high spatial frequencies. Spatial frequency discrimination was evaluated in 17 medicated male patients with… read more →
Han SD, Nestor PG, Shenton ME, Niznikiewicz M, Hannah G, McCarley RW Schizophr. Res. 2003 Jun;61(2-3):255-63 PMID: 12729877 Abstract We developed a computer model to simulate associative memory recall of patients with chronic schizophrenia. Model inputs consisted of words derived from normative data that differed in terms of connectivity and… read more →
Onitsuka T, Shenton ME, Kasai K, Nestor PG, Toner SK, Kikinis R, Jolesz FA, McCarley RW Arch. Gen. Psychiatry 2003 Apr;60(4):349-55 PMID: 12695311 Abstract BACKGROUND: The fusiform gyrus (FG), or occipitotemporal gyrus, is thought to subserve the processing and encoding of faces. Of note, several studies have reported that patients… read more →
Akdag SJ, Nestor PG, O’Donnell BF, Niznikiewicz MA, Shenton ME, McCarley RW Schizophr. Res. 2003 Nov;64(2-3):165-73 PMID: 14613681 Abstract Schizophrenia has long been associated with abnormal patterns of arousal that are thought to reflect disturbances in the reticular-activating system of the brain. Psychophysiological investigations of sensory responsivity have repeatedly demonstrated… read more →
Spencer KM, Nestor PG, Niznikiewicz MA, Salisbury DF, Shenton ME, McCarley RW J. Neurosci. 2003 Aug;23(19):7407-11 PMID: 12917376 Abstract Schizophrenia has been conceptualized as a failure of cognitive integration, and abnormalities in neural circuitry (particularly inhibitory interneurons) have been proposed as a basis for this disorder. We used measures of… read more →
Kubicki M, McCarley RW, Nestor PG, Huh T, Kikinis R, Shenton ME, Wible CG Neuroimage 2003 Dec;20(4):1923-33 PMID: 14683698 Abstract As a means toward understanding the neural bases of schizophrenic thought disturbance, we examined brain activation patterns in response to semantically and superficially encoded words in patients with schizophrenia. Nine… read more →