Shenton ME, Dickey CC, Frumin M, McCarley RW Schizophr. Res. 2001 Apr;49(1-2):1-52 PMID: 11343862 Abstract After more than 100 years of research, the neuropathology of schizophrenia remains unknown and this is despite the fact that both Kraepelin (1919/1971: Kraepelin, E., 1919/1971. Dementia praecox. Churchill Livingston Inc., New York) and Bleuler… read more →
Zahajszky J, Dickey CC, McCarley RW, Fischer IA, Nestor P, Kikinis R, Shenton ME Schizophr. Res. 2001 Jan;47(1):87-97 PMID: 11163548 Abstract Some cognitive disturbances accompanying schizophrenia may be due to abnormalities in the thalamus and components of the limbic system. The fornix is an important white-matter relay pathway connecting these… read more →
Wible CG, Kubicki M, Yoo SS, Kacher DF, Salisbury DF, Anderson MC, Shenton ME, Hirayasu Y, Kikinis R, Jolesz FA, McCarley RW Am J Psychiatry 2001 Jun;158(6):938-43 PMID: 11384903 Abstract OBJECTIVE: Previous research has noted functional and structural temporal lobe abnormalities in schizophrenia that relate to symptoms such as auditory… read more →
Nestor PG, O’Donnell BF, McCarley RW, Niznikiewicz M, Barnard J, Jen Shen Z, Bookstein FL, Shenton ME Schizophr. Res. 2002 Jan;53(1-2):57-66 PMID: 11728838 Abstract We applied partial least squares (PLS) as a novel multivariate statistical technique to examine neuropsychological correlates of magnetic resonance imaging (MRI) measures of brain volumes in… read more →
Nestor PG, Han SD, Niznikiewicz M, Salisbury D, Spencer K, Shenton ME, McCarley RW Biol Psychol 2001 Jul-Aug;57(1-3):23-46 PMID: 11454433 Abstract We view schizophrenia as producing a failure of attentional modulation that leads to a breakdown in the selective enhancement or inhibition of semantic/lexical representations whose biological substrata are widely… read more →
Salisbury DF, Shenton ME, Nestor PG, McCarley RW Clin Neurophysiol 2002 Mar;113(3):383-95 PMID: 11897539 Abstract OBJECTIVES: It is controversial whether a semantic processing bias for strong associates is present in schizophrenia, and unknown whether the language abnormalities observed in schizophrenia can be attributed to dysfunctions early or late in cognitive… read more →
Wible CG, Anderson J, Shenton ME, Kricun A, Hirayasu Y, Tanaka S, Levitt JJ, O’Donnell BF, Kikinis R, Jolesz FA, McCarley RW Psychiatry Res 2001 Nov;108(2):65-78 PMID: 11738541 Abstract The present study measured prefrontal cortical gray and white matter volume in chronic, male schizophrenic subjects who were characterized by a… read more →
Kubicki M, Westin CF, Maier SE, Frumin M, Nestor PG, Salisbury DF, Kikinis R, Jolesz FA, McCarley RW, Shenton ME Am J Psychiatry 2002 May;159(5):813-20 PMID: 11986136 Abstract OBJECTIVE: Disruptions in connectivity between the frontal and temporal lobes may explain some of the symptoms observed in schizophrenia. Conventional magnetic resonance… read more →
Anderson JE, Wible CG, McCarley RW, Jakab M, Kasai K, Shenton ME Schizophr. Res. 2002 Dec;58(2-3):123-34 PMID: 12409152 Abstract Previous magnetic resonance imaging (MRI) studies have reported various subtle brain abnormalities in schizophrenic patients, including temporal lobe abnormalities, which are of particular interest given the role of this brain region… read more →
Salisbury DF, Shenton ME, Griggs CB, Bonner-Jackson A, McCarley RW Arch. Gen. Psychiatry 2002 Aug;59(8):686-94 PMID: 12150644 Abstract BACKGROUND: Mismatch negativity (MMN) is an event-related brain potential that is sensitive to stimulus deviation from a repetitive pattern. The MMN is thought primarily to reflect the activity of sensory memory, with,… read more →
