Amanda Lyall, Ph.D.

Lyall_AmandaInvestigator, Assistant Professor


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Amanda E. Lyall is an Assistant Professor in the Departments of Psychiatry at Brigham and Women’s Hospital and at Massachusetts General Hospital, Harvard Medical School. She received her Ph.D. in 2014 in Neurobiology from the University of North Carolina – Chapel Hill where she worked in the lab of Dr. John Gilmore. Her dissertation research focused on utilizing MRI to characterize the developmental trajectories of cortical thickness and surface area in the first two years of life in both healthy and at-risk for schizophrenia infants. She joined the Psychiatry Neuroimaging Laboratory as a postdoctoral research fellow within the Clinical Research Training Program (T32) at Judge Baker Children’s Center in September of 2014, where she worked under the mentorship of Dr. Marek Kubicki.

Her research focuses on leveraging advanced neuroimaging techniques to understand the structural connectivity of the human brain in healthy and clinical populations, with a particular focus on the study of psychosis. Specifically, she aims to identify and describe the underlying biological mechanisms and trajectory of events surrounding transition to psychosis in schizophrenia and other associated psychotic disorders. Her present project employs a comprehensive cross-sectional and longitudinal multi-modal imaging paradigm (simultaneous MR-PET) combined with physiological, cognitive, and clinical data collection to construct a more complete picture of potential underlying biological factors related to resiliency in early stage psychosis patients.