In the absence of type III receptor, the transforming growth factor (TGF)-beta type II-B receptor requires the type I receptor to bind TGF-beta2

del Re E, Babitt JL, Pirani A, Schneyer AL, Lin HY J. Biol. Chem. 2004 May;279(21):22765-72 PMID: 14996829 Abstract Transforming growth factor beta (TGF-beta) ligands exert their biological effects through type II (TbetaRII) and type I receptors (TbetaRI). Unlike TGF-beta1 and -beta3, TGF-beta2 appears to require the co-receptor betaglycan (type… read more →